Hybrid pixel detectors permit noise hit free particle detection and imaging in a broad range of applications. These range from measurements and characterisation of background radiation in space, to spectroscopic X-ray imaging in clinics and all the way through to particle vertex detection in the most challenging environment of the LHC detectors. The Medipix Collaborations have developed and exploited this technology through the Timepix and Medipix family of ASICs. The Medipix3 Collaboration marked 20 years of activity in September 2025 with a full-day Symposium on Timepix and Medipix, an opportunity to review progress and to get an overview of the ongoing activities. Many of the presenters were clients of the commercial partners of the Collaborations highlighting the key role that private industry plays in bringing a technology which originated in High Energy Physics to a multitude of other scientific fields and applications. This presentation will firstly outline the key technical features of the Medipix and Timepix ASICs before overviewing some of the highlights of that day. The presentation will conclude with some personal reflections on some of the challenges faced and lessons learned.

Coffee will be served at 10:30