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KT and EP Detector Seminar: State of the art of positron emission tomography (PET) technology and current challenges


KT and EP Seminar: State of the art of positron emission tomography (PET) technology and current challenges
(Image: CERN)

When: 6 September 16:30
Speaker: Maurizio Conti, PET Physics and Reconstruction, Siemens Healthineers
Where: The seminar will take place on Zoom
For more information, please visit: https://indico.cern.ch/e/PET

A brief historical review of time-of-flight (TOF) positron emission tomography (PET) will be presented, including the recent developments in silicon photomultipliers (SiPM), which have resulted in improved TOF performance. The principles of TOF PET physics and a discussion of the technical and clinical advantages of TOF PET compared to conventional PET will be presented, including the concept of time resolution and its effect on TOF gain in signal-to-noise ratio (SNR), as well as properties such as reconstruction robustness to inconsistent data, convergence, and convergence speed. Other advanced reconstruction methods and innovations will be discussed, such as resolution recovery methods, data-driven methods for motion correction and the recent introduction of deep learning in various aspects of PET.

From the hardware point of view, we will review the most recent and exciting developments towards long axial field-of-view – or total-body – PET/CT scanners: design trade-off, characteristics and performance, challenges and advantages, including new applications enabled by very high-performance TOF PET scanners in the field of low-count imaging, theranostics and monoclonal antibody imaging, and dynamic and parametric imaging with simultaneous coverage of multiple organs.

Finally, we will briefly comment on the near future of PET and TOF PET in terms of possible technology developments and the need for fundamental research to push the field forward.


The EP Detector Seminars aim to make state-of-the-art presentations for scientists and engineers in the fields of particle detectors and their performances, detector engineering and infrastructure, detector electronics, detector applications in HEP and other fields. The aim of the Detector Seminars is to spread information on new developments and to stimulate in depth discussions within the detector community present at CERN.

Knowledge transfer at CERN could not happen without the knowledge exchange between experts in science, technology and industry. The Knowledge Transfer Seminars, launched in 2016, are a series of events showcasing how the novel technology and know-how developed at CERN translates into positive impact on society, by creating concrete solutions for industry across a wide range of fields: from medical technologies to aerospace, industry 4.0 and cultural heritage.

For information about the next Knowledge Transfer Seminar, sign up to our e-group at http://cern.ch/go/F9cX.